PrimePCR™ ddPCR™ Expression Probe Assay: REN, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052425; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037774
Chromosome Location:   1:204123969-204124078question
Amplicon Length:   80

Gene Information

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone releasevasoconstriction and increase in blood pressure. Renin an aspartyl protease cleaves angiotensinogen to form angiotensin I which is converted to angiotensin II by angiotensin I converting enzyme an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq Jul 2008]

Gene Symbol:   REN
Gene Name:   renin
Aliases:   FLJ10761, HNFJ2
RefSeq:   NC_000001.10 NG_012122.1 NT_004487.19
Ensembl:   ENSG00000143839
Entrez:   5972
UniGene:   Hs.3210
Chromosome Mapping:   1q32

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