PrimePCR™ ddPCR™ Expression Probe Assay: PARP1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052423; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037771
Chromosome Location:   1:226589925-226590048question
Amplicon Length:   94

Gene Information

This gene encodes a chromatin-associated enzyme poly(ADP-ribosyl)transferase which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation proliferation and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition this enzyme may be the site of mutation in Fanconi anemia and may participate in the pathophysiology of type I diabetes. [provided by RefSeq Jul 2008]

Gene Symbol:   PARP1
Gene Name:   poly (ADP-ribose) polymerase 1
Aliases:   ADPRT, ADPRT 1, ADPRT1, PARP, PARP-1, PPOL, pADPRT-1
RefSeq:   NC_000001.10 NT_167186.1
Ensembl:   ENSG00000143799
Entrez:   142
UniGene:   Hs.177766
Chromosome Mapping:   1q41-q42

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