PrimePCR™ ddPCR™ Expression Probe Assay: PKLR, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052411; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037747
Chromosome Location:   1:155260216-155260359question
Amplicon Length:   114

Gene Information

The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP which is the rate-limiting step of glycolysis. Defects in this enzyme due to gene mutations or genetic variations are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   PKLR
Gene Name:   pyruvate kinase, liver and RBC
Aliases:   PK1, PKL, PKR, PKRL, RPK
RefSeq:   NC_000001.10 NG_011677.1 NT_004487.19 NW_003315906.1
Ensembl:   ENSG00000143627
Entrez:   5313
UniGene:   Hs.95990
Chromosome Mapping:   1q21

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