PrimePCR™ ddPCR™ Expression Probe Assay: NR1I3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052369; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037671
Chromosome Location:   1:161200614-161200711question
Amplicon Length:   68

Gene Information

This gene encodes a member of the nuclear receptor superfamily and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance such as cytochrome P450 family members. Unlike most nuclear receptors this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus where it activates or represses target gene transcription. These ligands include bilirubin a variety of foreign compounds steroid hormones and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   NR1I3
Gene Name:   nuclear receptor subfamily 1, group I, member 3
Aliases:   CAR, CAR1, MB67, MGC150433, MGC97144, MGC97209
RefSeq:   NC_000001.10 NT_004487.19
Ensembl:   ENSG00000143257
Entrez:   9970
UniGene:   Hs.349642
Chromosome Mapping:   1q23.3

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