PrimePCR™ ddPCR™ Expression Probe Assay: PVRL4, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052365; exonic

Fluorophore:   HEX
List Price:    $201.00
Your Price:   Log In

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037663
Chromosome Location:   1:161042250-161042343question
Amplicon Length:   64

Gene Information

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1 an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq Jan 2011]

Gene Symbol:   PVRL4
Gene Name:   poliovirus receptor-related 4
Aliases:   DKFZp686K05193, EDSS1, LNIR, PRR4, nectin-4
RefSeq:   NC_000001.10 NG_028109.1 NT_004487.19
Ensembl:   ENSG00000143217
Entrez:   81607
UniGene:   Hs.492490
Chromosome Mapping:   1q22-q23.2

Number Description Download