PrimePCR™ ddPCR™ Expression Probe Assay: WRAP53, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052282; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037517
Chromosome Location:   17:7606668-7606820question
Amplicon Length:   123

Gene Information

This gene encodes an essential component of the telomerase holoenzyme complex a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin TERT and TERC other components of active telomerase and with small Cajal body RNAs (scaRNAs) which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq Mar 2011]

Gene Symbol:   WRAP53
Gene Name:   WD repeat containing, antisense to TP53
Aliases:   FLJ10385, TCAB1, WDR79
RefSeq:   NC_000017.10 NG_017013.1 NT_010718.16
Ensembl:   ENSG00000141499
Entrez:   55135
UniGene:   Hs.408312
Chromosome Mapping:   17p13.1

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