PrimePCR™ ddPCR™ Expression Probe Assay: SORD, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052212; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037400
Chromosome Location:   15:45366324-45366454question
Amplicon Length:   101

Gene Information

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses and together with aldose reductase (ALDR1; MIM 103880) makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM Jul 2010]

Gene Symbol:   SORD
Gene Name:   sorbitol dehydrogenase
Aliases:   SORD1
RefSeq:   NC_000015.9 NT_010194.17
Ensembl:   ENSG00000140263
Entrez:   6652
UniGene:   Hs.878
Chromosome Mapping:   15q15.3

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