PrimePCR™ ddPCR™ Expression Probe Assay: FBLN5, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052210; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037399
Chromosome Location:   14:92343892-92347648question
Amplicon Length:   118

Gene Information

The protein encoded by this gene is a secreted extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However its expression is reinduced in balloon-injured vessels and atherosclerotic lesions notably in intimal vascular smooth muscle cells and endothelial cells. Therefore the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa autosomal recessive cutis laxa type I (CL type I) and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq Jul 2008]

Gene Symbol:   FBLN5
Gene Name:   fibulin 5
Aliases:   ARMD3, DANCE, EVEC, FIBL-5, FLJ90059, UP50
RefSeq:   NC_000014.8 NG_008254.1 NT_026437.12
Ensembl:   ENSG00000140092
Entrez:   10516
UniGene:   Hs.332708
Chromosome Mapping:   14q32.1

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