PrimePCR™ ddPCR™ Expression Probe Assay: DHH, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052180; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037349
Chromosome Location:   12:49485036-49485131question
Amplicon Length:   66

Gene Information

This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq May 2010]

Gene Symbol:   DHH
Gene Name:   desert hedgehog
Aliases:   HHG-3, MGC35145
RefSeq:   NC_000012.11 NG_008973.1 NT_029419.12
Ensembl:   ENSG00000139549
Entrez:   50846
UniGene:   Hs.524382
Chromosome Mapping:   12q13.1

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