PrimePCR™ ddPCR™ Expression Probe Assay: LEF1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052133; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037268
Chromosome Location:   4:109010411-109084820question
Amplicon Length:   70

Gene Information

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq Oct 2009]

Gene Symbol:   LEF1
Gene Name:   lymphoid enhancer-binding factor 1
Aliases:   DKFZp586H0919, FLJ46390, TCF1ALPHA
RefSeq:   NC_000004.11 NT_016354.19 NG_015798.1
Ensembl:   ENSG00000138795
Entrez:   51176
UniGene:   Hs.555947
Chromosome Mapping:   4q23-q25

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