PrimePCR™ ddPCR™ Expression Probe Assay: HADHB, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052066; exonic

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037151
Chromosome Location:   2:26492861-26499945question
Amplicon Length:   80

Gene Information

This gene encodes the beta subunit of the mitochondrial trifunctional protein which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found; however their full-length nature is not known. [provided by RefSeq Jul 2008]

Gene Symbol:   HADHB
Gene Name:   hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
Aliases:   ECHB, MGC87480, MTPB, TP-BETA
RefSeq:   NC_000002.11 NG_007121.1 NG_007294.1 NT_022184.15
Ensembl:   ENSG00000138029
Entrez:   3032
UniGene:   Hs.515848
Chromosome Mapping:   2p23

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