PrimePCR™ ddPCR™ Expression Probe Assay: BCL2L10, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052055; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037132
Chromosome Location:   15:52401950-52402081question
Amplicon Length:   102

Gene Information

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4 BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2 BCL2L1/BCL-X(L) and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9 which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq Jul 2008]

Gene Symbol:   BCL2L10
Gene Name:   BCL2-like 10 (apoptosis facilitator)
Aliases:   BCL-B, Boo, Diva, MGC129810, MGC129811
RefSeq:   NC_000015.9 NT_010194.17
Ensembl:   ENSG00000137875
Entrez:   10017
UniGene:   Hs.283672
Chromosome Mapping:   15q21

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