PrimePCR™ ddPCR™ Expression Probe Assay: MAP2K5, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052048; exonic

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037119
Chromosome Location:   15:68099109-68099324question
Amplicon Length:   186

Gene Information

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3 as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq May 2011]

Gene Symbol:   MAP2K5
Gene Name:   mitogen-activated protein kinase kinase 5
Aliases:   HsT17454, MAPKK5, MEK5, PRKMK5
RefSeq:   NC_000015.9 NT_010194.17
Ensembl:   ENSG00000137764
Entrez:   5607
UniGene:   Hs.114198
Chromosome Mapping:   15q23

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