PrimePCR™ ddPCR™ Expression Probe Assay: IRF4, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052018; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037064
Chromosome Location:   6:408830-408970question
Amplicon Length:   111

Gene Information

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus t(6;14)(p25;q32) may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Aug 2010]

Gene Symbol:   IRF4
Gene Name:   interferon regulatory factor 4
Aliases:   LSIRF, MUM1
RefSeq:   NC_000006.11 NG_027728.1 NT_007592.15
Ensembl:   ENSG00000137265
Entrez:   3662
UniGene:   Hs.401013
Chromosome Mapping:   6p25-p23

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