PrimePCR™ ddPCR™ Expression Probe Assay: MRPL50, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051991; exonic

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037015
Chromosome Location:   9:104152909-104153041question
Amplicon Length:   103

Gene Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species the proteins comprising the mitoribosome differ greatly in sequence and sometimes in biochemical properties which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p 2q 5p and 10q. [provided by RefSeq Jul 2008]

Gene Symbol:   MRPL50
Gene Name:   mitochondrial ribosomal protein L50
Aliases:   FLJ20493, FLJ21990, MRP-L50
RefSeq:   NC_000009.11 NG_009774.1 NT_008470.19
Ensembl:   ENSG00000136897
Entrez:   54534
UniGene:   Hs.288224
Chromosome Mapping:   9q31.1

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