PrimePCR™ ddPCR™ Expression Probe Assay: IL10, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051966; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036967
Chromosome Location:   1:206941904-206942019question
Amplicon Length:   86

Gene Information

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines MHC class II Ags and costimulatory molecules on macrophages. It also enhances B cell survival proliferation and antibody production. This cytokine can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq May 2011]

Gene Symbol:   IL10
Gene Name:   interleukin 10
Aliases:   CSIF, IL-10, IL10A, MGC126450, MGC126451, TGIF
RefSeq:   NC_000001.10 NG_012088.1 NT_167186.1
Ensembl:   ENSG00000136634
Entrez:   3586
UniGene:   Hs.193717
Chromosome Mapping:   1q31-q32

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