PrimePCR™ ddPCR™ Expression Probe Assay: SCN7A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051964; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036962
Chromosome Location:   2:167334083-167343368question
Amplicon Length:   111

Gene Information

This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also the S4 segments which sense voltage changes have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist but the full-length natures of all of them remain unknown. [provided by RefSeq Dec 2011]

Gene Symbol:   SCN7A
Gene Name:   sodium channel, voltage-gated, type VII, alpha
Aliases:   SCN6A
RefSeq:   NC_000002.11 NT_005403.17
Ensembl:   ENSG00000136546
Entrez:   6332
UniGene:   Hs.596087
Chromosome Mapping:   2q21-q23

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