PrimePCR™ ddPCR™ Expression Probe Assay: MTHFS, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051953; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036944
Chromosome Location:   15:80137510-80137625question
Amplicon Length:   86

Gene Information

The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 510-methenyltetrahydrofolate a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq Jun 2011]

Gene Symbol:   MTHFS
Gene Name:   5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
Aliases:   FLJ30410, HsT19268
RefSeq:   NC_000015.9 NT_010194.17
Ensembl:   ENSG00000136371
Entrez:   10588
UniGene:   Hs.459049
Chromosome Mapping:   15q25.1

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