PrimePCR™ ddPCR™ Expression Probe Assay: HUS1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051944; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036928
Chromosome Location:   7:48018015-48018117question
Amplicon Length:   73

Gene Information

The protein encoded by this gene is a component of an evolutionarily conserved genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC) which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants. [provided by RefSeq Feb 2011]

Gene Symbol:   HUS1
Gene Name:   HUS1 checkpoint homolog (S. pombe)
Aliases:   hHUS1
RefSeq:   NC_000007.13 NT_007819.17
Ensembl:   ENSG00000136273
Entrez:   3364
UniGene:   Hs.152983
Chromosome Mapping:   7p13-p12

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