PrimePCR™ ddPCR™ Expression Probe Assay: KDELR2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051938; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036917
Chromosome Location:   7:6502574-6502723question
Amplicon Length:   120

Gene Information

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal usually lys-asp-glu-leu (KDEL) in animal cells and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes and binds the tetrapeptide-containing protein and returns it to the ER. In yeast the sorting receptor encoded by a single gene ERD2 is a seven-transmembrane protein. Unlike yeast several human homologs of the ERD2 gene constituting the KDEL receptor gene family have been described. KDELR2 was the second member of the family to be identified and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   KDELR2
Gene Name:   KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
Aliases:   ELP-1, ERD2.2, FLJ45532
RefSeq:   NC_000007.13 NT_007819.17
Ensembl:   ENSG00000136240
Entrez:   11014
UniGene:   Hs.654552
Chromosome Mapping:   7p22.1

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