PrimePCR™ ddPCR™ Expression Probe Assay: ITM2B, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051932; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036904
Chromosome Location:   13:48827946-48828068question
Amplicon Length:   93

Gene Information

Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein thereby increasing the size of the secreted peptide are associated with two neurogenerative diseases familial British dementia and familial Danish dementia. [provided by RefSeq Oct 2009]

Gene Symbol:   ITM2B
Gene Name:   integral membrane protein 2B
Aliases:   ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD
RefSeq:   NC_000013.10 NG_013069.1 NT_024524.14
Ensembl:   ENSG00000136156
Entrez:   9445
UniGene:   Hs.643683
Chromosome Mapping:   13q14.3

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