PrimePCR™ ddPCR™ Expression Probe Assay: CYP27A1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051909; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036863
Chromosome Location:   2:219677325-219677469question
Amplicon Length:   115

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis a rare autosomal recessive lipid storage disease. [provided by RefSeq Jul 2008]

Gene Symbol:   CYP27A1
Gene Name:   cytochrome P450, family 27, subfamily A, polypeptide 1
Aliases:   CP27, CTX, CYP27
RefSeq:   NC_000002.11 NG_007959.1 NT_005403.17
Ensembl:   ENSG00000135929
Entrez:   1593
UniGene:   Hs.516700
Chromosome Mapping:   2q33-qter

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