PrimePCR™ ddPCR™ Expression Probe Assay: AGT, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051890; exonic

Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036828
Chromosome Location:   1:230838316-230838416question
Amplicon Length:   71

Gene Information

The protein encoded by this gene pre-angiotensinogen or angiotensinogen precursor is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension and can cause renal tubular dysgenesis a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation and inflammatory bowel disease. [provided by RefSeq Jul 2008]

Gene Symbol:   AGT
Gene Name:   angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Aliases:   ANHU, FLJ92595, FLJ97926, SERPINA8
RefSeq:   NC_000001.10 NG_008836.1 NT_167186.1
Ensembl:   ENSG00000135744
Entrez:   183
UniGene:   Hs.19383
Chromosome Mapping:   1q42-q43

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