PrimePCR™ ddPCR™ Expression Probe Assay: GSTM3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051802; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036666
Chromosome Location:   1:110279482-110279614question
Amplicon Length:   103

Gene Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha kappa mu omega pi sigma theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds including carcinogens therapeutic drugs environmental toxins and products of oxidative stress by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq Nov 2008]

Gene Symbol:   GSTM3
Gene Name:   glutathione S-transferase mu 3 (brain)
Aliases:   GST5, GSTB, GSTM3-3, GTM3, MGC3310, MGC3704
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000134202
Entrez:   2947
UniGene:   Hs.2006
Chromosome Mapping:   1p13.3

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