PrimePCR™ ddPCR™ Expression Probe Assay: EIF2S1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051782; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036630
Chromosome Location:   14:67843170-67843304question
Amplicon Length:   105

Gene Information

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA EIF2 and GTP. EIF2 is composed of 3 nonidentical subunits the 36-kD EIF2-alpha subunit (EIF2S1) the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908) and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al. 1987 [PubMed 2948954]).[supplied by OMIM Feb 2010]

Gene Symbol:   EIF2S1
Gene Name:   eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
Aliases:   EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000134001
Entrez:   1965
UniGene:   Hs.151777
Chromosome Mapping:   14q23.3

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