PrimePCR™ ddPCR™ Expression Probe Assay: E2F5, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051769; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036609
Chromosome Location:   8:86121423-86121548question
Amplicon Length:   96

Gene Information

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP) a transactivation domain enriched in acidic amino acids and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107 but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   E2F5
Gene Name:   E2F transcription factor 5, p130-binding
Aliases:   E2F-5
RefSeq:   NC_000008.10 NT_008183.19
Ensembl:   ENSG00000133740
Entrez:   1875
UniGene:   Hs.445758
Chromosome Mapping:   8q21.2

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