PrimePCR™ ddPCR™ Expression Probe Assay: IDO1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051633; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036377
Chromosome Location:   8:39771410-39771519question
Amplicon Length:   80

Gene Information

This gene encodes indoleamine 23-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan L-tryptophan 5-hydroxy-tryptophan tryptamine and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense neuropathology immunoregulation and antioxidant activity. Through its expression in dendritic cells monocytes and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq Feb 2011]

Gene Symbol:   IDO1
Gene Name:   indoleamine 2,3-dioxygenase 1
Aliases:   IDO, IDO-1, INDO
RefSeq:   NC_000008.10 NG_028155.1 NT_167187.1
Ensembl:   ENSG00000131203
Entrez:   3620
UniGene:   Hs.840
Chromosome Mapping:   8p12-p11

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