PrimePCR™ ddPCR™ Expression Probe Assay: CCNT1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051525; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036180
Chromosome Location:   12:49083537-49083680question
Amplicon Length:   114

Gene Information

The protein encoded by this gene belongs to the highly conserved cyclin family whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit. [provided by RefSeq Jul 2008]

Gene Symbol:   CCNT1
Gene Name:   cyclin T1
Aliases:   CCNT, CYCT1, HIVE1
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000129315
Entrez:   904
UniGene:   Hs.92308
Chromosome Mapping:   12q13.11

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