PrimePCR™ ddPCR™ Expression Probe Assay: LOXL1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051507; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036150
Chromosome Location:   15:74240227-74241893question
Amplicon Length:   81

Gene Information

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation senescence tumor suppression cell growth control and chemotaxis to each member of the family. [provided by RefSeq Jul 2008]

Gene Symbol:   LOXL1
Gene Name:   lysyl oxidase-like 1
Aliases:   LOL, LOXL
RefSeq:   NC_000015.9 NG_011466.1 NT_010194.17
Ensembl:   ENSG00000129038
Entrez:   4016
UniGene:   Hs.65436
Chromosome Mapping:   15q24-q25,15q22

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