PrimePCR™ ddPCR™ Expression Probe Assay: MTRR, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051296; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5035775
Chromosome Location:   5:7869299-7871005question
Amplicon Length:   97

Gene Information

Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   MTRR
Gene Name:   5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Aliases:   MGC129643, MSR, cblE
RefSeq:   NC_000005.9 NG_008856.1 NT_006576.16
Ensembl:   ENSG00000124275
Entrez:   4552
UniGene:   Hs.481551
Chromosome Mapping:   5p15.31

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