PrimePCR™ ddPCR™ Expression Probe Assay: OPTN, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051242; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5035679
Chromosome Location:   10:13160908-13161019question
Amplicon Length:   82

Gene Information

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking vesicle trafficking and transcription activation through its interactions with the RAB8 huntingtin and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq Jul 2008]

Gene Symbol:   OPTN
Gene Name:   optineurin
Aliases:   ALS12, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
RefSeq:   NC_000010.10 NG_012876.1 NT_008705.16
Ensembl:   ENSG00000123240
Entrez:   10133
UniGene:   Hs.332706
Chromosome Mapping:   10p13

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