PrimePCR™ ddPCR™ Expression Probe Assay: CDKN2C, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051233; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5035662
Chromosome Location:   1:51439578-51439726question
Amplicon Length:   119

Gene Information

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6 and prevent the activation of the CDK kinases thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene which encode an identical protein have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   CDKN2C
Gene Name:   cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Aliases:   INK4C, p18, p18-INK4C
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000123080
Entrez:   1031
UniGene:   Hs.525324
Chromosome Mapping:   1p32

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