PrimePCR™ ddPCR™ Expression Probe Assay: CD207, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050923; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5035150
Chromosome Location:   2:71057361-71057455question
Amplicon Length:   65

Gene Information

The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq Aug 2010]

Gene Symbol:   CD207
Gene Name:   CD207 molecule, langerin
Aliases:   CLEC4K
RefSeq:   NC_000002.11 NT_022184.15
Ensembl:   ENSG00000116031
Entrez:   50489
UniGene:   Hs.199731
Chromosome Mapping:   2p13

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