PrimePCR™ ddPCR™ Expression Probe Assay: LOXL3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050863; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5035037
Chromosome Location:   2:74777369-74779467question
Amplicon Length:   96

Gene Information

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation senescence tumor suppression cell growth control and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   LOXL3
Gene Name:   lysyl oxidase-like 3
Aliases:   LOXL
RefSeq:   NC_000002.11 NG_012163.1 NT_022184.15
Ensembl:   ENSG00000115318
Entrez:   84695
UniGene:   Hs.469045
Chromosome Mapping:   2p13

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