PrimePCR™ ddPCR™ Expression Probe Assay: VEGFA, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050716; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034756
Chromosome Location:   6:43745231-43745321question
Amplicon Length:   61

Gene Information

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects including mediating increased vascular permeability inducing angiogenesis vasculogenesis and endothelial cell growth promoting cell migration and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants encoding either freely secreted or cell-associated isoforms have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of and in-frame with the first AUG leading to additional isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   VEGFA
Gene Name:   vascular endothelial growth factor A
Aliases:   MGC70609, MVCD1, VEGF, VPF
RefSeq:   NC_000006.11 NG_008732.1 NT_007592.15
Ensembl:   ENSG00000112715
Entrez:   7422
UniGene:   Hs.73793
Chromosome Mapping:   6p12

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