This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050552; exonic
This gene encodes the beta subunit of the glycine receptor which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease also known as hereditary hyperekplexia or congenital stiff-person syndrome a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq Oct 2009]