PrimePCR™ ddPCR™ Expression Probe Assay: FGF8, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050460; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034310
Chromosome Location:   10:103530268-103530357question
Amplicon Length:   60

Gene Information

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development cell growth morphogenesis tissue repair tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development organogenesis embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq Jul 2008]

Gene Symbol:   FGF8
Gene Name:   fibroblast growth factor 8 (androgen-induced)
Aliases:   AIGF, FGF-8, HBGF-8, KAL6, MGC149376
RefSeq:   NC_000010.10 NT_030059.13 NG_007151.1
Ensembl:   ENSG00000107831
Entrez:   2253
UniGene:   Hs.57710
Chromosome Mapping:   10q24

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