This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050446; exonic
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis integrin-mediated signal transduction and cell transformation. Several alternatively spliced transcript variants of this gene have been described but the full-length nature of some variants has not been determined. [provided by RefSeq Jul 2008]