PrimePCR™ ddPCR™ Expression Probe Assay: KDELR1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050332; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034091
Chromosome Location:   19:48892858-48892964question
Amplicon Length:   77

Gene Information

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal usually lys-asp-glu-leu (KDEL) in animal cells and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes and binds the tetrapeptide-containing protein and returns it to the ER. In yeast the sorting receptor encoded by a single gene ERD2 which is a seven-transmembrane protein. Unlike yeast several human homologs of the ERD2 gene constituting the KDEL receptor gene family have been described. The protein encoded by this gene was the first member of the family to be identified and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq Jul 2008]

Gene Symbol:   KDELR1
Gene Name:   KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
Aliases:   ERD2, ERD2.1, HDEL, PM23
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000105438
Entrez:   10945
UniGene:   Hs.515515
Chromosome Mapping:   19q13.3

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