PrimePCR™ ddPCR™ Expression Probe Assay: KCNQ2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049621; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5032905
Chromosome Location:   20:62076179-62076707question
Amplicon Length:   96

Gene Information

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC) also known as epilepsy benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   KCNQ2
Gene Name:   potassium voltage-gated channel, KQT-like subfamily, member 2
Aliases:   BFNC, BFNS1, EBN, EBN1, EIEE7, ENB1, HNSPC, KCNA11, KV7.2, KVEBN1
RefSeq:   NC_000020.10 NT_011333.6 NG_009004.1
Ensembl:   ENSG00000075043
Entrez:   3785
UniGene:   Hs.161851
Chromosome Mapping:   20q13.3

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