PrimePCR™ ddPCR™ Expression Probe Assay: WISP2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049466; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5032627
Chromosome Location:   20:43356333-43356452question
Amplicon Length:   90

Gene Information

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain von Willebrand factor type C module thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue and may play an important role in modulating bone turnover. [provided by RefSeq Jul 2008]

Gene Symbol:   WISP2
Gene Name:   WNT1 inducible signaling pathway protein 2
Aliases:   CCN5, CT58, CTGF-L
RefSeq:   NC_000020.10 NT_011362.10
Ensembl:   ENSG00000064205
Entrez:   8839
UniGene:   Hs.592145
Chromosome Mapping:   20q13.12

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