PrimePCR™ ddPCR™ Expression Probe Assay: HNMT, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0040406; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5030695
Chromosome Location:   2:138722052-138722168question
Amplicon Length:   87

Gene Information

In mammals histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   HNMT
Gene Name:   histamine N-methyltransferase
Aliases:   HMT, HNMT-S1, HNMT-S2
RefSeq:   NC_000002.11 NT_022135.16 NG_012966.1
Ensembl:   ENSG00000150540
Entrez:   3176
UniGene:   Hs.42151
Chromosome Mapping:   2q22.1

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