This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0040381; exonic
Alkylglycerol monooxygenase (AGMO; EC 188.8.131.52) cleaves the O-alkyl bonds of ether lipids which are essential components of brain membranes and function in cell signaling and other critical biologic processes. The reaction catalyzed by AGMO is dependent on tetrahydrobiopterin a metabolite structurally related to the vitamins folic acid and riboflavin (summary by Watschinger et al. 2010 [PubMed 20643956]).[supplied by OMIM Feb 2011]