PrimePCR™ ddPCR™ Expression Probe Assay: ADAM15, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0040360; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5030624
Chromosome Location:   1:155030531-155030727question
Amplicon Length:   76

Gene Information

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain a disintegrin-like domain as well as a EGF-like domain. Through its disintegrin-like domain this protein specifically interacts with the integrin beta chain beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq Jul 2008]

Gene Symbol:   ADAM15
Gene Name:   ADAM metallopeptidase domain 15
Aliases:   MDC15
RefSeq:   NC_000001.10 NG_027536.1 NT_004487.19
Ensembl:   ENSG00000143537
Entrez:   8751
UniGene:   Hs.312098
Chromosome Mapping:   1q21.3

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