PrimePCR™ ddPCR™ Expression Probe Assay: SLC26A5, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0039506; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5030122
Chromosome Location:   7:103051928-103053450question
Amplicon Length:   77

Gene Information

This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Nov 2009]

Gene Symbol:   SLC26A5
Gene Name:   solute carrier family 26, member 5 (prestin)
Aliases:   DFNB61, MGC118886, MGC118887, MGC118888, MGC118889, PRES
RefSeq:   NC_000007.13 NT_007933.15 NG_023055.1
Ensembl:   ENSG00000170615
Entrez:   375611
UniGene:   Hs.585146
Chromosome Mapping:   7q22.1

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