PrimePCR™ ddPCR™ Expression Probe Assay: PLAGL1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0039179; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5029718
Chromosome Location:   6:144263432-144263530question
Amplicon Length:   69

Gene Information

This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties and thus thought to function as a tumor suppressor. In addition overexpression of this gene during fetal development is believed to underlie the rare disorder transient neonatal diabetes mellitus (TNDM). This gene is imprinted with preferential expression of the paternal allele in many tissues however biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms have been found for this gene. [provided by RefSeq Oct 2010]

Gene Symbol:   PLAGL1
Gene Name:   pleiomorphic adenoma gene-like 1
Aliases:   DKFZp781P1017, LOT1, MGC126275, MGC126276, ZAC, ZAC1
RefSeq:   NG_016174.1 NC_000006.11 NG_009384.1 NT_025741.15
Ensembl:   ENSG00000118495
Entrez:   5325
UniGene:   Hs.444975
Chromosome Mapping:   6q24-q25

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