PrimePCR™ ddPCR™ Expression Probe Assay: LAMTOR3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0039134; exonic

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5029673
Chromosome Location:   4:100803063-100803208question
Amplicon Length:   116

Gene Information

This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein and binds specifically to MAP kinase kinase MAP2K1/MEK1 MAP kinase MAPK3/ERK1 and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq Aug 2011]

Gene Symbol:   LAMTOR3
Gene Name:   late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Aliases:   MAP2K1IP1, MAPBP, MAPKSP1, MP1, Ragulator3
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000109270
Entrez:   8649
UniGene:   Hs.433332
Chromosome Mapping:   4q23

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