PrimePCR™ ddPCR™ Expression Probe Assay: RASD1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0033330; Exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5029152
Chromosome Location:   17:17398375-17398526question
Amplicon Length:   122

Gene Information

This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON and a nuclear adaptor protein FE65 which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Sep 2011]

Gene Symbol:   RASD1
Gene Name:   RAS, dexamethasone-induced 1
Aliases:   AGS1, DEXRAS1, MGC:26290
RefSeq:   NC_000017.10 NG_028074.1 NT_010718.16
Ensembl:   ENSG00000108551
Entrez:   51655
UniGene:   Hs.25829
Chromosome Mapping:   17p11.2

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