PrimePCR™ ddPCR™ Expression Probe Assay: HMGA2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0033041; Exonic

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5029087
Chromosome Location:   12:66218268-66218409question
Amplicon Length:   112

Gene Information

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion amplification and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   HMGA2
Gene Name:   high mobility group AT-hook 2
RefSeq:   NC_000012.11 NG_016296.1 NT_029419.12
Ensembl:   ENSG00000149948
Entrez:   8091
UniGene:   Hs.505924
Chromosome Mapping:   12q15

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