PrimePCR™ ddPCR™ Expression Probe Assay: BCL11A, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0032938; Exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5029074
Chromosome Location:   2:60773185-60773332question
Amplicon Length:   118

Gene Information

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene in part through its interaction with BCL6. During hematopoietic cell differentiation this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   BCL11A
Gene Name:   B-cell CLL/lymphoma 11A (zinc finger protein)
Aliases:   BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856
RefSeq:   NC_000002.11 NG_011968.1 NT_022184.15
Ensembl:   ENSG00000119866
Entrez:   53335
UniGene:   Hs.370549
Chromosome Mapping:   2p16.1

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